摘要
目的:探讨产前MRI在胎儿胼胝体发育不全(ACC)中的应用价值。方法:回顾性分析64例行头部MRI并诊断为ACC的胎儿,孕周23+1~38+1周,中位数孕周29周,采用三维容积内插快速T1WI序列、单次激发快速自旋回波序列和平衡式稳态自由进动序列扫描,分析MRI表现。结果:64例ACC胎儿中,胼胝体完全缺如者有49例,胼胝体部分缺如者15例。所有的ACC均伴有侧脑室形态异常或扩大。伴颅内其它畸形的胎儿28例。结论:胎儿MRI可以明确诊断ACC及其类型,是否伴发颅内其他畸形,对于胎儿胼胝体发育不全产前诊断及预后评价具有重要价值。
Objective:To explore the MRI diagnostic value on fetal agenesis of corpus callosum(ACC).Methods:Brain MRI data of 64 fetuses diagnosed as ACC were prospectively analysed.MRI studies were performed between 23+1 to 38+1 pregnancy week,average 29 weeks.The MRI protocol included three dimensional volume interpolation T1-weighted sequence,single-shot fast spin echo sequence,and balance fast field echo sequence.MR imaging findings were analyzed.Results:In 64 cases of ACC,there were complete agenesis in 49 cases and partial agenesis in 15 cases.All ACC cases had abnormal or enlarged lateral ventricles.Additionally,28 cases of ACC had other associated brain abonormalities.Conclusion:Fetal MRI can clearly diagnose ACC,the types of ACC and other associated brain abonormalities.Fetal MRI is of great value in the prenatal diagnosis and prognosis evaluation of fetal ACC.
作者
叶芷君
宁刚
李学胜
YE Zhi-jun;NING Gang;LI Xue-sheng(Key Laboratory of Birth Defects and Related Diseases of Women and Children(Sichuan University),Ministry of Education,Chengdu 610041,China)
出处
《放射学实践》
北大核心
2018年第6期617-621,共5页
Radiologic Practice
关键词
胎儿发育
磁共振成像
诊断
Fetal development
Magnetic resonance imaging
Diagnosis