布鲁氏菌病患者生活质量与临床症状的相关性分析

Correlation between quality of life and clinical symptoms of brucellosis patients

目的探讨布鲁氏菌病患者生活质量与不同临床症状的相关性,为临床医护人员实施干预提供理论依据。方法采用单纯随机抽样方法,使用一般资料调查表、疼痛评分表(NRS)及健康状况调查表(SF-36),对某传染病医院2017年1月-2017年6月收住入院的498例布鲁氏菌病患者进行问卷调查,分析临床症状与生活质量的相关性。结果 498例调查对象中,出现疼痛患者与无痛患者比较,在生理机能、生理职能、躯体疼痛、社会功能、情感职能及精神健康6个领域有统计学意义(P均<0.01);出汗患者与无出汗患者相比,在生理机能、生理职能、躯体疼痛(P均<0.01)及情感职能4个领域有统计学意义(P<0.05);疲乏无力患者与无疲乏无力患者比较,生理机能、生理职能、躯体疼痛(P均<0.01)及情感职能领域差异有统计学意义(P<0.05)。疼痛与生理功能、生理职能和躯体疼痛呈中度相关(r=0.380、0.325、0.460,P均<0.01),与社会功能及心理健康领域呈弱相关(r=0.281、0.136,P均<0.01);出汗与生理功能、生理职能、躯体健康、总体健康、精力、社会功能、情感职能和心理健康这8个维度呈负相关;疲乏无力与生理职能及躯体疼痛(r=-0.117、-0.127,P均<0.01)、生理功能及情感职能(r=-0.102、-0.102,P均<0.05)呈弱相关。疼痛评分和疼痛分级与患者的生活质量呈负相关,疼痛评分越高、疼痛程度越严重,生活质量量表得分越低(P均<0.01)。结论不同疾病症状的发生对患者的生活质量各个领域的影响有所不同,其生活质量水平与疾病症状及疼痛程度相关,提示临床医疗工作者应重视其对患者生活质量的影响,采取针对性的干预措施。

Objective To explore the correlation between quality of life and clinical symptoms in brucellosis patients,and provide reference for clinical medical staff.Methods Using the method of simple random sampling,498 patients with brucellosis were investigated in The Xinjiang Uygur Autonomous Region Sixth People′s Hospital from January to June in 2017 by questionnaires,which included the general information questionnaire,pain score table and health status questionnaire（SF-36）,the relationship between the quality of life and clinical symptoms of patients was assessed.Results Among 498 brucellosis patients,there were differences in physiological function,role-physical,physical pain,social function,emotional intelligence and mental health in comparison with painless and pain patients（P〈0.01 for all）.Sweating patients are different from non-sweating patients in 4 fields：physiological function,rolephysical,somatic pain（P〈0.01 for all）and emotional function（P〈0.05）.Compared with patients without fatigue,asthenia patients are different in physiological function,role-physical,physical pain（P〈0.01 for all）and emotional function（P〈0.05）.The pain is moderate correlated with physiological function,role-physical and somatic pain（r=0.380,0.325,0.460,P〈0.01 for all）,and was weakly correlated with social function and mental health（r=0.281,0.136,P〈0.01 for all）.Sweating is negatively correlated with the 8 dimensions which are physiological function,role-physical,body pain,general health,vitality,social function,emotional function and mental health.Whether fatigue or not is weakly correlated with role-physical and body pain（r=-0.117,-0.127,P〈0.01 forall）,physiological function and emotional function（r=-0.102,-0.102,P〈0.05 for all）.Conclusion The symptoms of different diseases have different effects on the quality of life of the patients.The quality of life is related to the symptoms of disease and the degree of pain,which suggests that the clinical medical workers should pay attention to their influence on the quality of life of the patients and take pertinent intervention measures.