全麻复合硬膜外麻醉对胃癌根治术的麻醉效果以及对患者术后TNF-α和IL-6水平的影响

Effect of General Anesthesia Combined with Epidural Anesthesia on Radical Gastrectomy for Gastric Cancer and Its Effect on Postoperative TNF-alpha and IL-6 Levels

目的:对胃癌根治术患者实施全麻复合硬膜外麻醉的效果及对其肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)水平的影响。方法:将2016年1月~2017年1月接收的114例胃癌患者分作A、B两组各57例,A组行全麻,B组行全麻复合硬膜外麻醉,比较并分析其结果。结果:术后B组T淋巴细胞水平与A组对比有显著差异,且TNF-α、IL-6水平低于A组,有统计学意义(P<0.05)。结论:胃癌根治术中应用全麻复合硬膜外麻醉的效果显著,价值颇高。

Objective：To evaluate the effect of general anesthesia combined with epidural anesthesia on radical gastrectomy for gastric cancer and its effect on postoperative TNF-alpha and IL-6 levels.Methods：114 patients undergoing radical gastrectomy From January 2016 to January 2017 were randomly divided into group A and group B,with 57 cases in each group.Group A was given general anesthesia and group B was given general anesthesia combined with epidural anesthesia.The clinical effect were analyzed retrospectively.Results：There was a significant difference in the T lymphocyte level between group B and group A after operation,and the levels of TNF-IL-6 and IL-6 were lower than that of group A,with statistical significance（P〈0.05）.Conclusion：General anesthesia combined with epidural anesthesia is effective and valuable in radical gastrectomy.