不同剂量肉苁蓉在复方苁蓉通便汤中量效关系的临床研究

Clinical research on dose-effect relationship of different doses of cistanche in compound Cong rong tongbian decoction

目的:探讨不同剂量肉苁蓉在复方苁蓉通便汤中治疗阳虚便秘的临床疗效。方法:将60例临床明确诊断为阳虚便秘的患者随机分为3组,小剂量组用肉苁蓉10 g加入苁蓉通便汤,中剂量组用肉苁蓉20 g加入苁蓉通便汤,大剂量组用肉苁蓉30 g加入苁蓉通便汤;治疗7天后观察比较三组患者的排便时间。结果:治疗后三组患者排便时间均缩短,小、高剂量组间比较差异显著,有统计学意义(P<0.01);小剂量组与中剂量组比较,差异有统计学意义(P<0.05)。结论:研究结果表明,苁蓉通便汤可以缩短排便时间,而且随着肉苁蓉剂量的增加效果增强。

Objective：To observe the clinical effect of different doses of cistanche in compound Congrong tongbian decoction on constipation of yang deficiency.Methods：60 cases of patients,who were diagnosed clinically clearly as constipation of yang deficiency,were randomly divided into 3 groups.The small-dose group was treated with 10 g cistanche added into Congrong tongbian decoction;the middle-dose group with 20 g cistanche added into Congrong tongbian decoction;the high-dose group with 30 g cistanche added into Congrong tongbian decoction.After 7 days of treatment,the defecation time of each patient in 3 groups was observed and compared.Results：After treatment,the defecation time of each patient in 3 groups was shortened.The comparative difference between small-and high-dose groups was significant,and with statistical significance（P〈0.01）.The omparative difference between small-and middle-dose groups was statistically significant（P〈0.05）.Conclusion：The result of research has shown that Congrong tongbian decoction can shorten the defecation time and its effect is strengthened with the increase of cistanche dose.