多囊卵巢综合征中医证候要素横断面研究

Cross-sectional study on TCM syndrome elements of polycystic ovary syndrome

目的:探讨PCOS患者证候要素,为其临床辨证论治提供参考。方法:对182例PCOS患者的中医症状、舌象、脉象等四诊信息进行横断面调查,采用因子分析方法了解其证候要素分布规律。结果:特征根>1的公因子有18个,经同质性合并,共提炼出10个病性类证候要素:痰湿、阳虚、血瘀、气虚、气滞、气郁、阴虚、血虚、精亏、热火。3个病位类证候要素:肾脏、脾脏和肝脏,最终累及的靶器官是胞宫。结论:因子分析是确定PCOS常见证候要素的有效方法,PCOS患者最多见的证候要素为痰湿、阳虚、血瘀,病症的靶位器官为胞宫,涉及肾、脾、肝脏。为PCOS的中医辨论提供了依据。

Objective：To explore the syndrome elements of PCOS patients,and to provide the reference for clinical syndrome differentiation and treatment.Methods：For 182 cases of PCOS patients,TCM symptoms,tongue pictures and pulse conditions etc.informations of four diagnostic methods were investigated cross-sectionally.The distribution law of their syndrome elements was found out by factor analysis method.Results：There were 18 common factors of eigenvalues 1.Through homogeneity consolidation,10 syndrome elements of disease nature type were extracted totally,i.e.phlegm-dampness,yang deficiency,blood stagnation,qi deficiency,qi stagnation,qi depression,yin deficiency,blood deficiency,essence damage and fire-heat.Also 3 syndrome elements of disease location type：i.e.kidney,spleen and liver;the finally involved target organ was uterus.Conclusion：The factor analysis is an effective method to determine the common syndrome elements of PCOS.The most common syndrome elements of PCOS patients are phlegm-dampness,yang deficiency,blood stagnation.The target organ of this disease is uterus.Kidney,spleen and liver are involved.This study provides the basis for TCM syndrome differentiation of PCOS.