综合管理方案对支气管肺发育不良极低体重出生儿出院后短期生存状况的影响

Effect of integrated program management on short-term survival status of very low birth weight infants with bronchopulmonary dysplasia

目的:探讨综合管理方案对支气管肺发育不良(BPD)极低体重出生儿出院后短期生存状况的影响。方法:选择2010年1月-2014年12月某院新生儿重症监护室收治的64例支气管肺发育不良极低体重患儿,根据管理方案的不同分为观察组与对照组,其中应用综合管理方案的36例BPD患儿为观察组,应用传统管理方案的28例BPD患儿为对照组。比较2组患儿之间的肺功能和神经系统发育情况、呼吸道症状发生率和再住院次数。结果:2组患儿住院期间治疗情况以及呼吸道症状发生率比较差异无统计学意义(P>0.05);观察组神经系统发育情况及校正年龄3月龄时的肺功能明显优于对照组,再住院率明显低于对照组,差异有统计学意义(P<0.05)。结论:应用综合管理方案治疗支气管肺发育不良极低体重出生儿有利于改善患儿肺功能以及促进神经系统发育,能够有效降低患儿再住院率,改善预后,值得临床推广应用。

Objective： To study the effect of integrated program management on the short-term survival status of very low birth weight infants with bronchopulmonary dysplasia（ BPD）. Methods： Clinical data of 64 very low birth weight infants with BPD in the Neonatal Intensive Care Unit of a hospital were enrolled and divided into an integrated program management group（ observation group,36 cases）and a traditional management group（ control group,28 cases）. The lung function,neurodevelopment,the number of rehospitalization and respiratory symptoms of the two groups were compared and analyzed. Results： There was no significant difference in respiratory symptoms as well as in the treatment condition during hospitalization between the two groups（ P〈0.05）.The development of nervous system and lung function at 3 months of the corrected age in the observation group were significantly better than those in the control group（ P〈0.05）. The rate of rehospitalization of the observation group was significantly lower than that of the control group（ P〈0. 05）.Conclusion： The integrated program management could improve the lung function,promote the nervous system development,reduce rehospitalization for the very low birth weight infants with BPD. It is worthy of clinical application.