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氨甲环酸联合利伐沙班在老年股骨转子间骨折患者围手术期的治疗体会 被引量:3

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摘要 目的:探讨氨甲环酸联合利伐沙班治疗老年股骨转子间骨折减少出血及预防静脉血栓的临床疗效。方法:选择行闭合复位PFNA内固定的老年股骨转子间骨折患者随机分为氨甲环酸联合利伐沙班组(观察组,40例)与低分子肝素组(对照组,40例),记录2组患者的总失血量、隐性失血量、输血量、输血例数、术后1天血红蛋白下降值、血凝指标及术后2周下肢静脉血栓的发生情况。结果:观察组总失血量、隐性失血量、输血量、输血例数、输血率、血红蛋白下降值均低于对照组,差异有统计学意义(P<0.05);术后2组血凝指标比较差异无统计学意义(P>0.05);2组患者均无严重出血倾向,术后2周下肢超声检查均未发现深静脉血栓。结论:氨甲环酸联合利伐沙班应用于老年股骨转子间骨折闭合复位PFNA内固定围手术期,可有效减少出血量,降低输血率并预防下肢深静脉血栓形成。
出处 《淮海医药》 CAS 2018年第4期480-483,共4页 Journal of Huaihai Medicine
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