摘要
Dear Editor, Gliomas are the most frequent primary tumors of the central nervous system, accounting for more than 60% of all brain tumors （Wang and Bettegowda, 2015）. Among them, glio-blastoma multiforme （GBM） is the most common aggressive glioma, and the average survival rate remains low （Chen et al., 2015）. The standard combination of surgery and radio-therapy or chemotherapy can only extend the progression-free survival time for 12-18 months, with a high risk of re-currence （Li et al., 2008）. In addition, the incidence of GBM has increased annually by 1%-2% in the past years （Louis et al., 2007）. Therefore, a precise early diagnosis of GBM is crucial for the early determination of appropriate therapeutic strategies.
Dear Editor,Gliomas are the most frequent primary tumors of the central nervous system,accounting for more than 60%of all brain tumors(Wang and Bettegowda,2015).Among them,glioblastoma multiforme(GBM)is the most common aggressive glioma,and the average survival rate remains low(Chen et al.,2015).The standard combination of surgery and radiotherapy or chemotherapy can only extend the progressionfree survival time for 12–18 months,with a high risk of recurrence(Li et al.,2008).In addition,the incidence of
