Th17／Treg细胞免疫失衡在低氧性肺动脉高压疾病中的作用研究进展

Research advance on the role of Th17/Treg cellular immune imbalance in hypoxic pulmonary hypertension

低氧性肺动脉高压（HPH）是一种进展极快的疾病，目前尚无有效治疗方法，因此寻找有效干预靶点是值得研究的方面。前期研究发现T细胞免疫介导的炎症反应参与HPH的发生发展，并有进一步研究表明Th17／Treg细胞免疫失衡参与HPH的发病机制，本文将对这些研究作一总结。

Hypoxic pulmonary hypertension （HPH） is a rapidly developing disease and there is no effective treatment method at present. So it is worth studying to find effective intervention targets. Previous studies have found that T-cell-mediated inflammation is involved in the occurrence and development of HPH, and further studies have shown that Th17/Treg cell immune imbalance is involved in the pathogenesis of HPH. This paper will make a summary of these studies.