体外膜肺氧合在儿童脓毒性休克的应用

Extracorporeal membrane oxygenation in children with septic shock

脓毒性休克是脓毒症中最严重的类型，尽管国内外指南给予了详尽的治疗建议，但仍有部分脓毒性休克患者对治疗无反应，病情迅速进展而发展为多脏器功能衰竭导致死亡。新近脓毒性休克的指南和共识推荐ECMO可作为儿童脓毒性休克的最后一道防线。但这些患儿何时实施ECMO治疗，ECMO置管方式以及预后还存在争议。本文就ECMO在儿童脓毒性休克的应用进行阐述。

Septic shock is the most serious type of sepsis. Despite detailed treatment recommenda- tions at domestic and abroad guidelines, some patients with septic shock have no response to treatment, and progress rapidly and develop into multiple organ failure leading to death. The recent guidelines and consensus of septic shock recommended extracorporeal membrane oxygenation （ECMO）as the last resort rescue for chil- dren with septic shock. However, worldwide consensus for ECMO application in children with septic shock is not available at the present time. Clinical conditions that ECMO should be initiated, ECMO catheterization method and prognosis of children received ECMO support are still controversial. The aim of this article was to review ECMO application in children with septic shock.