中西医结合治疗慢性肾炎58例临床观察

Clinical effect of integrated traditional Chinese and Western medicine therapy in treatment of chronic nephritis: An analysis of 58 cases

目的:观察中西医结合治疗慢性肾炎的临床疗效。方法:将112例慢性肾炎患者随机分为治疗组58例和对照组54例,对照组予以西医常规治疗,治疗组在对照组治疗的基础上加用虫类药物治疗,治疗8周后观察2组患者临床症状、肾功能、24h尿蛋白定量、血液流变学等变化。结果:2组临床症状积分、24h尿蛋白定量、血肌酐及血液流变学各项指标治疗前后组内比较及治疗后组间(除血浆黏度外)比较,差异均有统计学意义(P<0.05)。结论:运用虫类药结合西医常规治疗慢性肾炎可以有效缓解患者的临床症状,改善血液循环,减轻蛋白尿,保护肾功能。

Objective： To investigate the clinical effect of integrated traditional Chinese and Western medicine therapy in the treatment of chronic nephritis. Methods： A total of 112 patients with chronic nephritis were randomly divided into treatment group with 58 patients and control group with 54 patients. The patients in the control group were given conventional Western medicine treatment,and those in the treatment group were given worm medicine in addition to the treatment in the control group. The changes in clinical symptoms,renal function,24-hour urinary protein quantitation,and hemorheological parameters were observed after 8 weeks of treatment. Results： Both groups had significant changes in clinical symptom score,24-hour urinary protein quantitation,serum creatinine,and hemorheological parameters after treatment（P〈0.05）. After treatment,there were significant differences between the two groups in all these indices except plasma viscosity（P〈0.05）. Conclusion： Worm medicine combined with conventional Western medicine treatment for chronic nephritis can effectively relieve patients＇ clinical symptoms,improve blood circulation,alleviate proteinuria,and protect renal function.