结直肠Dieulafoy病的诊断和治疗进展

Progress in diagnosis and treatment of colorectal Dieulafoy's disease

Dieulafoy病,即黏膜下恒径动脉破裂出血,是消化道大出血少见而又致命的病因之一,可发生在整个消化道,其中4%位于结直肠,结直肠的病变则最常见于直肠和盲肠,目前病因及发病机制尚不明确.结直肠Dieulafoy病的临床表现为无先兆的、反复发作的、致死性的便血,间歇期可无任何临床表现,目前首选内镜下进行诊断及治疗,但由于操作难度、临床特点等因素,对于Dieulafoy病的诊断和治疗仍是个难题.本文就结直肠Dieulafoy病的病理、病因、发病机制、诊断和治疗进展作一概述.

Dieulafoy＇s lesion, also named calibre persistent submucosal artery, is one of the rare and fatal causes of gastrointestinal bleeding, which can occur throughout the digestive tract. About 4% of Dieulafoy＇s lesions arelocated in the colon and rectum, especially in the rectum, cecum, and ascending colon. At present, the etiology and pathogenesis of colorectal Dieulafoy＇s disease are still not completely clear. The main clinical manifestation of colorectal Dieulafoy＇s disease is recurrent and massive hematochezia, and there may be no clinical manifestation during the intermittent period of the hemorrhage. The diagnosis and treatment of Dieulafoy＇s disease mainly rely on endoscopy, but due to the operating difficulties, clinical characteristics, and other factors, the treatment and diagnosis of this disease remain a challenge to clinicians. In this paper, we will discuss the pathology, etiology, pathogenesis, pathology, diagnosis, and treatment of colorectal Dieulafoy＇s lesion.