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中国肾移植受者抗HLA抗体监测及处理的临床共识 被引量:6

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摘要 肾移植受者术前及术后均可能产生抗HLA抗体,这些抗体可介导排斥反应,主要包括以下3种情况:(1)预存抗体介导的超急性排斥反应:受者体内因输血、妊娠及前次移植等原因而形成的预存抗供者HLA抗体,这些抗体与移植抗原结合后可迅速激活补体,损伤血管内皮,导致严重的血管炎、血栓形成及组织缺血坏死。
出处 《中华器官移植杂志》 CAS CSCD 北大核心 2018年第5期300-303,共4页 Chinese Journal of Organ Transplantation
基金 湖北省技术创新专项(重大项目)(2017ACA096)
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