经皮球囊肺动脉瓣成形术治疗肺动脉瓣狭窄临床分析

Percutaneous Balloon Pulmonary Valvuloplasty for Pulmonary Valve Stenosis

目的评估经皮球囊肺动脉瓣膜成形术(PBPV)治疗肺动脉瓣狭窄(PS)的安全性和有效性。方法 2010年12月—2014年12月间共32例单纯肺动脉瓣狭窄患者行PBPV治疗;完善超声心动图、心电图、X线胸片检查,行右心室造影及右心导管检查并完成PBPV术;分析其临床资料、安全性及治疗效果。结果 32例患者中6例双球囊扩张,26例采用单球囊,均扩张成功。肺动脉瓣跨瓣压差由术前(74±22)mm Hg(1 mm Hg=0.133 k Pa)下降为术后(28±16)mm Hg,差异有统计学意义(t=11.188,P<0.05)。结论 PBPV术用于单纯性肺动脉瓣狭窄疗效显著,安全可靠,并发症少,患者痛苦小,可作为该类患者的首选治疗方法。

Objective To evaluate the safety and efficacy of percutaneous balloon pulmonary valvuloplasty（PBPV） in the treatment of pulmonary valve stenosis（PS）. Methods From December 2010 to December 2014, 32 patients with pulmonary valve stenosis were treated with PBPV alone; echocardiography, electrocardiogram, X-ray examination, right ventricular angiography and right heart catheterization were performed and PBPV was performed. Analyze its clinical data, safety, and treatment effects. Results Of the 32 patients, 6 were double-balloon dilatation and 26 were single-balloons, and all were successfully expanded. Pulmonary valve transvalvular pressure difference from preoperative（74±22）mm Hg（1 mm Hg = 0.133 k Pa） decreased to postoperative（28±16）mm Hg, the difference was statistically significant（t =11.188, P〈0.05）. Conclusion PBPV is a simple, safe and reliable method for the treatment of simple pulmonary valve stenosis. It has less complications and less pain. It can be used as the first choice for this type of patients.