高频超声对2型糖尿病周围神经病变患者腓总神经的临床观察

Clinical observation of peroneus communis nerve in type 2 diabetic peripheral neuropathy patients by high-frequency ultrasound

目的探讨高频超声观察2型糖尿病周围神经病变患者腓总神经的临床价值。方法选取62例2型糖尿病患者,分为周围神经病变组32例和无周围神经病变组30例,并选取同期28例非糖尿病患者作为正常对照组,应用高频超声观察各组腓管处腓总神经图像变化,测量并比较腓总神经前后径、横径及横截面积,并结合神经电生理检查进行相关性分析。结果周围神经病变组腓总神经前后径、横径及横截面积较无周围神经病变组和正常对照组均增大,差异均有统计学意义(均P<0.05)。周围神经病变组患者腓总神经的横截面积与腓总神经感觉传导速度呈负相关(r=-0.552,P<0.01)。结论高频超声能显示2型糖尿病周围神经病变患者腓总神经的异常改变,为临床诊断提供客观依据。

Objective To explore the clinical value of peroneus communis nerve in type 2 diabetes peripheral neuropathy（DPN） patients observed by high-frequency.Methods Sixty-two patients with type 2 diabetes were divided into the DPN group（including 32 patients with diabetic peripheral neuropathy）and non-DNP group（including 30 patients without diabetic peripheral neuropathy）.28 non diabetic patients were enrolled as the control group.All the subjects were examined by high-frequency ultrasound.The diameter,anteroposterior diameter and cross-sectional area were measured and compared among the three groups.The correlation between neural eletrophysiological examination and high frequency ultrasound examination was analyzed.Results The diameter,anteroposterior diameter and cross-sectional area of DNP group were higher than those of nonDNP group and control group（all P〈0.05）.The cross-sectional area of DNP group was negative correlated with motor neural conduction velocity（r=-0.552,P〈0.01）.Conclusion High-frequency ultrasound can clearly show the changes of peroneus communis nerve in type 2 diabetes peripheral neuropathy patients,and provide objective base for clinical diagnosis.