氨氯地平、氯沙坦钾氢氯噻嗪治疗老年难治性高血压效果

The Effect of Amlodipine and Chlorosartan Potassium Hydrochlorothiazide in the Treatment of Elderly Refractory Hypertension

目的探讨氨氯地平、氯沙坦钾氢氯噻嗪联合应用于老年难治性高血压的临床治疗效果。方法对照组经氯沙坦钾氢氯噻嗪治疗,研究组经氯沙坦钾氢氯噻嗪、氨氯地平联合治疗,两组均连续治疗3个月为宜。记录两组老年难治性高血压患者治疗前后舒张压(DBP)、收缩压(SBP)变化情况。结果两组治疗前SBP、DBP水平对比,P均>0.05,治疗后研究组SBP、DBP水平下降幅度优于对照组,P均<0.05。结论利用氨氯地平、氯沙坦钾氢氯噻嗪联合治疗老年难治性高血压效果显著,有利于保障患者生活质量、生命安全。

Objective To investigate the clinical efcacy of amlodipine and chlorsartan potassium hydrochlorothiazide in the treatment of refractory hypertension in old age. Methods The control group was treated with potassium hydrochlorothiazide, and the research group was treated with potassium hydrochlorothiazide and amlodipine, and the two groups were treated for 3 months consecutively. The diastolic blood pressure （DBP） and systolic blood pressure （SBP） were recorded in two groups of patients with refractory hypertension. Results Before treatment, SBP and DBP level of the two groups were all P 〉 0.05, and the decrease of SBP and DBP in the group after treatment was better than that in the control group, P 〈 0.05. Conclusion The combination of amlodipine and chlorosartan potassium hydrochlorothiazide is effective in the treatment of elderly refractory hypertension, which is benefcial to ensure the quality of life and life safety of patients.