二甲双胍治疗胰岛素抵抗型多囊卵巢综合征的临床疗效

The Clinical Efficacy of Metformin in the Treatment of Insulin Resistant Polycystic Ovary Syndrome

目的探讨常规调养联合二甲双胍治疗胰岛素抵抗型多囊卵巢综合征的应用效果。方法纳入90例胰岛素抵抗型多囊卵巢综合征患者以数字表法分组。对照组给予单一常规调养治疗,观察组则给予常规调养联合二甲双胍治疗。比较两组胰岛素抵抗型多囊卵巢综合征治疗效果。结果观察组胰岛素抵抗型多囊卵巢综合征治疗效果高于对照组,P<0.05;干预前两组血糖、胰岛素和性激素相关指标相近,P>0.05;干预后观察组血糖、胰岛素和性激素相关指标优于对照组,P<0.05。结论常规调养联合二甲双胍治疗胰岛素抵抗型多囊卵巢综合征的应用效果确切,可有效改善血糖、胰岛素和性激素相关指标。

Objective To investigate the effect of conventional therapy combined with metformin in the treatment of insulin resistant polycystic ovary syndrome. Methods 90 patients with insulin resistance polycystic ovary syndrome were grouped by digital table. The control group was given a single routine treatment, while the observation group was given conventional treatment with metformin. The therapeutic efect of two groups of insulin resistant polycystic ovary syndrome was compared. Results The treatment effect of insulin resistance polycystic ovary syndrome in observation group was higher than that in control group, P 〈 0.05; The indexes of blood glucose, insulin and sex hormone were similar between the two groups before intervention, P 〉 0.05; After intervention, blood glucose, insulin and sex hormones in the observation group were better than those in the control group, P 〈 0.05. Conclusion Conventional therapy combined with metformin is efective in the treatment of insulin resistant polycystic ovary syndrome. It can efectively improve blood glucose, insulin and sex hormones.