2015—2017年我院住院药房麻醉药品使用情况分析

Analysis on the use of narcotic drugs in hospital pharmacies of a hospital in Tianjin from 2015-2017

目的:了解2015—2017年本院住院药房麻醉药品的使用情况,为临床合理使用麻醉药品提供参考。方法:收集本院2015年1月—2017年12月9 309张麻醉药品使用处方并进行统计,应用用药频度(DDDs)、日均费用(DDC)、药物利用指数(DUI)对用药情况进行分析。结果:本院2015—2017年麻醉药品销售呈相对稳定趋势,2016年较2015年降低15.75%,2017年较2016年增长15.77%。2015—2017年盐酸舒芬太尼一直保持较高销售水平,枸橼酸舒芬太尼注射液(1 ml∶50μg)的销量呈持续增长趋势,逐渐取代枸橼酸芬太尼注射液(2 ml∶0.1 mg),盐酸羟考酮缓释片逐渐取代盐酸羟考酮注射液。2015—2017年麻醉药品DDDs排名为枸橼酸舒芬太尼注射液(1 ml∶50μg)>枸橼酸芬太尼注射液(2 ml∶0.1 mg)>瑞芬太尼,盐酸羟考酮缓释片DDDs处于持续增长趋势,而盐酸羟考酮注射液、盐酸哌替啶注射液、可待因片呈逐渐下降趋势,其他药物DDDs浮动相对稳定。2015—2017年麻醉药品不合理用药指数(DUI)有下降趋势,但枸橼酸舒芬太尼注射液(1 ml∶50μg)、枸橼酸芬太尼注射液(2 ml∶0.1 mg)、瑞芬太尼的DUI一直处于较高水平。盐酸羟考酮注射液、阿桔片、盐酸哌替啶注射液的DDC值在2015—2017年一直保持的较高的趋势。结论:本院麻醉药品用药存在不合理的现象,应加强加大对麻醉药品的监管力度。

Objective： to understand the use of narcotic drugs in inpatient dispensary of Tianjin XXX hospital in 2015—2017,so as to provide reference for clinical rational use of narcotic drugs. Methods： The prescription and statistics of 6309 narcotic drugs used in our hospital from January 2015 to January 2017 were collected,and the use of drug use frequency（ DDDs）,daily average cost（ DDC）,and drug use index（ DUI） were used to analyze the drug use. Results： The sales of narcotic drugs in our hospital showed an increasing trend year by year. 2016 decreased by 15. 75% compared with 2015,while 2017 increased by 15. 77% compared with 2016. 2015—2017 years of remifentanil has maintained a high level of sales,Fentanyl Citrate Injection（ 1 ml∶ 50 μg）sales in a continuous growth trend,gradually replacing Fentanyl Citrate Injection（ 2 ml∶ 0. 1 mg）,Oxycodone Hydrochloride Prolonged-release Tablets gradually replaced hhcl injection. 2015—2017 years of narcotic drug DDDs ranked Fentanyl Citrate Injection（ 1 ml∶ 50 μg） Fentanyl Citrate Injection（ 2 ml∶ 0. 1 mg） remifentanil,Oxycodone Hydrochloride Prolonged-release Tablets DDDs was in the continuous growth trend,while oxycodone hydrochloride injection,Pethidine Hydrochloride Injection,codeine tablets showed a gradual decline,other drugs. The DDDs floating is relatively stable. In the past 2015—2017 years,the irrational drug use index（ DUI） of narcotic drugs has declined,but Fentanyl Citrate Injection（ 1 ml∶ 50 μg）,Fentanyl Citrate Injection（ 2 ml∶ 0. 1 mg） and remifentanil DUI have been at a high level. The DDC value of oxycodone hydrochloride,oranges,Pethidine Hydrochloride Injection and Bucinnazine Hydrochloride Injection has maintained a high trend for 2015—2017 years. Conclusion： Irrational use of narcotic drugs in our hospital should be strengthened and supervision on narcotic drugs should be strengthened.