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复方苦参注射液联合化疗对胃肠道恶性肿瘤的疗效及对患者生活质量的影响 被引量:5

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摘要 目的:探究复方苦参注射液联合化疗治疗胃肠道恶性肿瘤对患者免疫功能和生活质量的影响。方法:选取本院2015年2月—2017年2月收治的胃肠道恶性肿瘤患者90例作为实验对象,随机将其分成两组,对照组(45例)结直肠癌患者使用采用FOLFOX6化疗方案、胃癌患者使用XELOX化疗方案;观察组(45例)在对照组基础上加用复方苦参注射液治疗:复方苦参注射液20 ml溶入250 ml氯化钠注射液中静脉滴注,1次/d,连续治疗14 d。对比两组患者治疗有效率,使用生活质量简表(SF-36)评估两组患者治疗前后的生活质量情况。结果:观察组治疗总有效率为77.78%,远高于对照组的57.78%(P<0.05);治疗前两组患者SF-36量表中躯体功能、生理职能、疼痛、活力、社会功能、精神健康、情绪角色和总体健康评分差异无统计学意义(P>0.05),治疗后2组患者各维度评分均显著提升,与治疗前对比差异有统计学意义(P<0.05),治疗后组间对比各维度评分观察组均显著高于对照组(P<0.05)。结论:复方苦参注射液联合化疗治疗胃肠道恶性肿瘤可显著提升患者的生存质量,值得推广。
作者 岳晓兰
出处 《天津药学》 2018年第4期47-48,共2页 Tianjin Pharmacy
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