中文版MoCA和MoCA-B在诊断遗忘型轻度认知功能障碍中的应用

Application of Chinese MoCA and MoCA-B in the Diagnosis of Amnesia Mild Cognitive Impairment

目的比较中文北京版蒙特利尔认知评估量表(MoCA)和蒙特利尔认知评估基础量表(MoCA-B)在诊断筛查遗忘型轻度认知障碍(aMCI)中的作用。方法以2016年9月至2017年5月在西南医科大学附属医院神经内科就诊的患者为检查对象,筛选出符合纳入标准33例aMCI患者及31名健康对照者,分别进行MoCA和MoCA-B量表检测,对两量表诊断aMCI的敏感性和特异性进行比较,进一步分析MoCA-B在诊断aMCI中的作用和特点。结果以26分作为分界值,MoCA和MoCA-B诊断aMCI的特异性分别为70.97%和93.55%,MoCA-B的特异性显著高于MoCA,差异具有统计学意义(P<0.05);敏感性分别为51.52%和30.30%,两组比较差异无统计学意义(P>0.05)。结论与MoCA相比,MoCA-B在诊断筛查aMCI过程中较少出现误诊,具有较高的特异性。

Objective To compare the role of Chinese Beijing version of Montreal Cognitive Assessment scale（MoCA） and Montreal basic Cognitive Assessment scale （ MoCA-B ） in the diagnosis and screening of amnesia mild cognitive impairment （aMCI）. Methods Patients in the Department of Neurology, affiliated Hospital of Southwest Medical UniversiU from September 2016 to May 2017 were selected as study subjects. Among them,33 aMCI patients who met the inclusion criteria and 31 healthy controls were selected and tested by MoCA and MoCA-B scales respectively. The sensitivity and specificity of the two scales in di- agnosing aMCI were compared,and the role and characteristics of MoCA-B in the diagnosis of aMCI were further analyzed. Results Using 26 points as the cut-off value,the specificity of MoCA and MoCA-B in diagnosing aMCI was 70. 97% and 93.55% respectively, and the specificity of MoCA-B was significantly higher than that of MoCA, and the difference was statistically significant （P 〈 0. 05）;The sensitivities were 51.52% and 30. 30% respectively, and there was no significant difference between the two groups （P 〉 0. 05）. Conclusion Compared with MoCA, MoCA-B has less misdiagnosis and higher specificity in the diagnosis and screening of aMCI.