前列腺体积参数与良性前列腺增生临床参数的相关性研究

A study of prostate volume,prostate weight and the clinical parameters in BPH patients

目的 探讨前列腺体积参数与良性前列腺增生 (BPH)临床参数之间的相关性 方法 回顾性分析 80例资料完整的BPH行开放性手术患者的相关资料。 结果 前列腺体积 (6 7.8± 33.9)ml,移行带体积 (42 .8± 2 4.9)ml,移行带指数 (0 .6 199± 0 .140 0 ) ,前列腺症状评分 (2 5 .0± 5 .5 ) ,标本重 (42 .7± 2 5 .1)g ,PSA(4.0 5± 3.90 )ng/ml。手术标本重量与前列腺体积 (r=0 .872P <0 .0 0 1)、移行带体积 (r =0 .97P <0 .0 0 1)、移行带指数 (r=0 .44 9P <0 .0 0 1)呈显著正相关关系 ;PSA与前列腺体积 (r=0 .2 13P =0 .0 33)、移行带体积 (r=0 .2 2 4P =0 .0 17)、移行带指数 (r =0 .314P =0 .0 36 )呈正相关 ;IPSS与前列腺体积 (r=0 .0 10P =0 .72 5 )无相关 ,与移行带体积 (r=0 .314P =0 .0 36 )、移行带指数 (r=0 .32 1P =0 .0 0 1)呈正相关。尿潴留与非尿潴留组 :前列腺体积 (P >0 .0 5 )差别无显著性意义 ,移行带体积 (P <0 .0 5 )、移行带指数 (P <0 .0 5 )、PSA(P <0 .0 1)组间差别有显著性意义。 结论 前列腺体积参数中移行带体积、移行带指数与临床症状、梗阻程度关系密切 ,能更好地反映BPH的严重程度 ;移行带体积能较好预测增生腺体的大小 ;随着移行带指数增高 ,尿潴留的危险性相应增加。

Objective To study the prostate volume,prostate weight and the clinical parameters in BPH patients and to investigate the interrelationships between the relevant parameters. Methods The complete data of 80 cases of BPH underwent open surgery were reviewed and analyzed.SPSS software was uesd to make the statistical analysis. Results The volume of surgical specimen has been positively correlated with PV( r=0.872,P <0.001),TZV( r=0.970,P <0.001),and TZI( r=0.449, P <0.001).There was also a positive correlation between PSA with PV ( r=0.213,P <0.05),TZV ( r=0.224,P <0.05)and TZI ( r=0.314,P <0.05).IPSS has no correlation with PV( r=0.010,P =0.725),but was positively correlated with TZV( r=0.314,P <0.05)and TZI( r=0.321,P <0.001).There were significant differences in TZV(49.6±22.0?29.4±19.6, P =0.018),TZI(0.745±0.091?0.481±0.022, P =0.014)and PSA(5.24±3.60?3.26±2.92, P =0.009) between patients with urinary retention and without retention, but not so in PV(69.7±27.2?66.2±24.3, P =0.086). Conclusions Of all the parameters of prostatic hyperplasia, TZV and TZI have been much more correlated with the clinical symptoms and the extent the of obstruction, can reflecting better the degree of BPH than PV. TZV of the surgical specimen can more accurately indicate the volume of the hyperplastic gland.The risk of urinary retention becoms higher along with higher TZI.