期刊文献+

氧化应激对猪肠道损伤机制的研究进展 被引量:10

Research Progress of Oxidative Stress on Mechanism of Intestinal Damage in Pigs
下载PDF
导出
摘要 畜牧业生产过程中出现的种畜繁殖障碍、幼畜成活率低和发病率高、畜产品品质下降等都与氧化应激有关,氧化应激已经成为动物健康与营养研究的热点。本文对肠道氧自由基产生来源、氧化应激影响肠上皮细胞增殖分化机制及猪生产中氧化应激对肠道氧化损伤进行了综述。 In the process of animal husbandry production,reproductive failure,lowsurvival rate and high incidence of young animals,and the decline in quality of animal products are all related to oxidation stress. Oxidative stress has become a hot topic in animal health and nutrition research. This article reviewed the source of oxygen free radicals in gut,the mechanism of intestinal epithelial cell proliferation and differentiation induced by oxygen free radicals and oxidative stress in pig production.
作者 陈凤鸣 陈佳亿 彭伟 韦良开 李颖慧 黄兴国 CHEN Fengming, CHEN Jiayi, PENG Wei ,WEI Liangkai, LI Yinghui, HUANG Xingguo(College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, Chin)
出处 《动物营养学报》 CAS CSCD 北大核心 2018年第8期2887-2893,共7页 CHINESE JOURNAL OF ANIMAL NUTRITION
基金 国家自然科学基金项目(31772617) 国家重点研发计划项目(2017YFD0500500)
关键词 氧自由基 氧化应激 肠上皮细胞 oxygen free radicals oxidative stress intestinal epithelial cells
  • 相关文献

参考文献1

二级参考文献28

  • 1Akiyama H, Lyons J P, Mori-Akiyama Y, et a1. Interactions between Sox9 and beta-catenin control chondrocyte differentia?tion[J]. Genes Dev , 2004 (8): 1072-1087.
  • 2Andreu P, Peignon G, Slomianny C, et a1. A genetic study of the role of the Wnt/beta-catenin signalling in Paneth cell differ?entiation[J]. Dev BioI, 2008 (324): 288-296.
  • 3Bastide P, Darido C, Pannequin J, et a1. Sox9 regulates cell pro?liferation and is required for Paneth cell differentiation in the in?testinal epithelium[J]. J Cell Bio!, 2007 (78): 635-648.
  • 4Batlle E, Henderson J T, Beghtel H, et a1. Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by con?trolling the expression of EphB/EphrinB[J]. Cell, 2002 (Ill): 251-263.
  • 5Barker N, Van Es J H, Kuipers J, et a1. Identification of stem cells in small intestine and colon by marker gene Lgr5[J]. Na?ture, 2007 (449): 1003-1007.
  • 6Bettess M D, Dubois N, Murphy M J, et a1. C-Myc is required for the formation of intestinal crypts but dispensable for homeo?stasis of the adult intestinal epithelium[J]. Mol Cell Biol , 2005 (25): 7868-7878.
  • 7Chen X, Johns D C, Geim D E, et a1. Kruppel-like factor 4 (gut?enriched Kruppel-likefactor) inhibits cell proliferation by bloc?king G1/S progression of the cell cycle[J]. J Biol Chern, 2001 (276): 30423-30428.
  • 8Finch A J, Soucek L, Junttila M R, et a1. Acute overexpression of Myc in intestinal epithelium recapitulates some but not all the changes elicited by Wnt/beta-catenin pathway activation[J]. Mol Cell BioI, 2009 (29): 5306-5315.
  • 9Gerbe F, van Es J H, Makrini L, et a1. Distinct ATOH 1 and Neu?rog3 requirements define tuft cells as a new secretory cell type in the intestinal epithelium[J]. Cell BioI, 2011(192) :767-780.
  • 10Ghaleb A M, McConnell B B, Kaestner K H, et al. Altered intesti?nal epithelial homeostasis in mice with intestine-specific deletion of the Kruppel-like factor 4 gene[J]. Dev Biol, 2011 (349): 310-320.

共引文献1

同被引文献192

引证文献10

二级引证文献80

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部