基于分子生物学的不同环境因子影响水华藻类生长和产毒的研究进展

A review on factors affecting algal growth and toxin production based on molecular biology

近年来,水体富营养化引起的有害水华暴发已经成为全球性的环境问题.PCR技术和高通量技术的发展及其在藻类研究领域中的应用,促进了藻类基因组学和转录组学的发展,丰富了藻类基因信息.从分子生物学角度研究有害藻华频发和藻毒素产生的机理成为国内外的研究热点.本文对近年来从分子生物学角度研究有害藻类产生的物理、化学及其他影响因素进行综述,总结不同环境因素对藻类生长和产毒影响的研究现状及进展,有助于从基因表达及调控角度研究藻华的形成及藻类的产毒机制,阐明其与环境因子的关系,具有显著的科学和实际意义.

Harmful algal blooms（ HABs） induced by eutrophication have become a global environmental problem recently. With the development of PCR and high-throughput technology,its application in algae genomics and transcriptomics has been promoted. It enriches the algae gene information and provides new method to further study the mechanisms of algal blooms and toxin production. On the perspective of molecular biology,the mechanism of HABs and algal toxins production have become a worldwide hotspot. The environmental factors,such as the physical,chemical and others,are reviewed to find its effects on algae growth and toxin production based on molecular biology. The research progress based on molecular biology is also summarized. This review could be helpful to investigating the mechanisms of algal blooms and toxin production from the perspective of molecular biology. It is significant to clarify their relationship from the perspective of gene expression.