精准纳米气体治疗研究进展

Progress of Precision Nanomedicine-mediated Gas Therapy

精准纳米气体治疗具有低毒高效等特性,作为一种新兴的疾病治疗手段受到越来越多的关注。研究表明,纳米气体治疗不仅能在特定疾病部位选择性杀死癌细胞,还能保护正常细胞。本文总结了国际最新研究成果,对精准纳米气体治疗的最新研究进展进行了总结归纳和展望。首先,阐述了纳米气体治疗的治疗作用和特点;然后,总结了实现精准纳米气体治疗的主要途径,包括靶向气体传输、可控气体释放、医学成像引导和监控气体治疗、基于治疗性气体的多模式联合治疗等;最后,对纳米气体治疗存在的问题和发展前景做出了总结和展望。

The precision nanomedicine-mediated gas therapy as an emerging and promising therapy strategy has received increasing attention, due to its low toxicity and high efficacy. Recent studies show that the nanomedicine-mediated gas therapy can not only kill cancer cells in specific diseased sites, but also protect normal cells. This review summarizes and reviews the most recent progress of the nanomedicine-mediated gas therapy. We introduce the therapeutic effects and characteristics of the nanomedicine-mediated gas therapy firstly, and then review several main routes to realize the precision nanomedicine-mediated gas therapy, including targeted gas delivery, controlled gas release, biomedical imaging guidance-monitoring of gas therapy, multi-model combined therapy based on therapeutic gases, and so on, and finally summarize the present existing issues and the prospects of further development in the gas therapy field.