2012年至2016年我院多重耐药菌监测情况回顾性分析

Retrospective Analysis of Surveillance of Polydrug-resistant Bacteria in a Maternal and Child Health Institution From 2012 to 2016

目的分析2012年至2016年我院多重耐药菌流行及分布情况,为多重耐药菌引起院感的防控提供依据。方法选取2012年1月至2016年12月间我院收治的所有住院患者中多重耐药菌感染412例临床资料,回顾性描述耐药菌种类分布、科室分布、标本分布及季节分布。结果共检出多重耐药菌412株,占0.6%,主要为产ESBLs大肠埃希菌、产ESBLs肺炎克雷伯菌、耐甲氧西林金黄色葡萄球菌(MRSA)及耐甲氧西林凝固酶阴性葡萄球菌(MRSCON),送检的标本主要为痰液、咽拭、脓汁、尿液,检出的病例主要集中在儿内科NICU(27.39%)和PICU(20.21%)区域,外科病区(24.73%)。多重耐药菌检出在第2季度呈上升趋势。结论针对上述分布特点,该医院应做好手卫生和环境日常清洁消毒及终末消毒预防和降低多重耐药菌院感的发生。

Objective This study describes the prevalence and distribution of multi-drug resistant organ-isms （MDRO） at women and children Hospital to provide evidence for the prevention and control of drug resis-tance. Methods This study retrospectively analyzed the data of MDRO in women and children Hospital Chinese from 2012 to 2016. The prevalence of MDRO distribution trends including distribution of department, pathogenic bacteria, inspection area were described and seasonal distribution. Results MDRO is identified in 412 patients and the detection rate was 0. 6 %. The top three multi - drug resistant bacteria are Extended - spectrumβ - lac-tamase （ESBL） Escherichia coli, methicillin - resistant staphylococcus aureus （MRSA）, methicillin - resistant coagulase-negative （MRSCON）. The primary multi-drug resistant bacterium （MRSCON） had an increased tendency. Sputum, secretion and urine were the main submission specimens. The departments of neonatal inten-sive care unit（NICU） （27.43 % ）, pediatric intensive care unit department（PlCU） （20.63 % ） and Surgery Ward （24.51%）had the highest detection rate. The detection of MDRO showed an increasing trend in the second quarter. Conclusion According to the above distribution characteristics, the hospital should do a good job in cleaning and disinfection of hand hygiene and environment, and prevent and reduce the occurrence of multidrug - resistant bacteria.