血管内皮损伤标志物在肺血栓栓塞症中相关研究进展

Research progress of vascular endothelial injury markers in pulmonary thromboembolism

肺血栓栓塞症是临床常见危重症，病死率高。因其发病诱因和危险因素复杂多样，且临床表现缺乏特异性，易漏诊和误诊。肺血栓栓塞的发病原因主要有血管内皮细胞损伤、血液高凝、静脉血液淤滞，而血管内皮损伤是主要病因。该研究对血管内皮损伤标志物在肺血栓栓塞症中的相关研究进展做一综述。

Pulmonary thromboembolism is a common clinical critical disease with high mortality. Because of its pathogenesis and risk factors are complex and diverse, and the lack of specific clinical manifestations, pulmonary thromboem-bolism is easily never？ diagnosed and misdiagnosed. Pulmonary thromboembolism results from a combination of endothelial injury, blood hypercoagulability/blood stasis, and endothelial injury is the main mechanism of the body for developing pulmonary thromboembolism. This article reviews the research progress of vascular endothelial injury markers in pulmonary thromboembolism.