薛建国从中医视角运用5型磷酸二脂酶抑制剂体会

XUE Jianguo’s Experience in Application of Phosphodiesterase Type 5 Inhibitors from Perspective of Traditonal Chinese Medicine

5型磷酸二脂酶抑制剂（PDE5i）是治疗男性勃起功能障碍的一线经典用药,薛建国教授从中医视角分析总结了PDE5i的药性、功效及作用特点,认为PDE5i味辛性平,主入肝经,功能疏肝通络起痿,对肝郁、血瘀型阳痿患者疗效最佳,辨证属于肝肾阴亏、肝阳上亢、气血不足的患者要慎用PDE5i。薛老师还提出了相应的中医配合疗法,为中医临床更好地运用PDE5i提供了借鉴。

Phosphodiesterase type 5 inhibitors（PDE5 i） is the first-line classic drug for the treatment of erectile dysfunction（ED）. Professor XUE Jianguo analyzed the pharmacological properties,efficacy and action characteristics of PDE5 i from the perspective of traditional Chinese medicine.He believes that PDE5 i is pungent in taste and plain in nature. It mainly enters the liver meridian and its function is dispersing the liver,removing obstruction in collaterals and erecting impotence. It has the best effect for patients with impotence of liver stagnation or blood stasis syndrome. However,patients with impotence of liver and kidney yin deficiency,liver yang hyperactivity and qi and blood deficiency should used PDE5 i cautiously. The corresponding treatment methods of traditional Chinese medicine were proposed by Mr. XUE,providing experience for better application of PDE5 i in traditional Chinese medicine clinical practice.