摘要
目的:研究莱菔子的化学成分。方法:利用多种色谱技术对莱菔子中化合物进行分离、纯化,通过理化性质测定、光谱分析等鉴定其结构。结果:从莱菔子乙醇提取物中分离鉴定出10个化合物,分别为:β-谷甾醇(1)、2-O-β-D呋喃果糖基-α-D-异吡喃糖酯(2)、反式-芥子酸乙酯(3)、3,4-二羟基-2-氧-吲哚-3-乙腈(4)、反式-芥子酸(5)、4-羟基-3-吲哚醛(6)、β-D-(3-芥子酰基)果糖基-α-D-(6-芥子酰基)葡萄糖苷(7)、阿魏酸(8)、反式-芥子碱硫氰酸盐(9)、5-羟甲基糠醛(10)。结论:化合物4、6为首次从莱菔子中分离得到。
Objective:To study the chemical composition of Laifuzi(Raphani Semen). Methods:Various chromatographic techniques were used to isolate and purify the compounds in Raphani Semen and the structure of the compounds was identified by physicochemical property and spectroscopic analysis. Results:A total of10 compounds were isolated from the ethanol extract of Raphani Semen,including β-daucosterol(1),2-O-β-Dfructofuranosyl-α-D-allopyranose(2),trans-(2 E)-ethyl-3-(4-hydroxy-3,5-dimethoxyphenyl)acrylate(3),2-(3,4-Dihydroxy-2-oxoindolin-3-yl) acetonitrile(4),trans-sinapic acid(5),4-hydroxyindole-3-carboxaldehyde(6),β-D-(3-sinapoyl) frueofuranosyl-a-D-(6-sinapoyl) glueopyranosid(7),ferulic acid(8),trans-sinapine bisulfate(9),5-hydromethyl furaldehyde(10). Conclusion:Compound 4 and 6 were first isolated from Raphani Semen.
作者
张茜
周洪雷
李民
朱立俏
张玲
蔡梅超
何珊
李传厚
倪琳琳
ZHANG Xi;ZHOU Honglei;LI Min;ZHU Liqiao;ZHANG Ling;CAI Meichao;HE Shan;LI Chuanhou;NI Linlin(Pharmaceutical College of Shandong University of Traditional Chinese Medicine,Jinan 250355,China;Shandong Dong'e Ejiao Group Co.,Ltd.,Liaocheng 252201,China)
出处
《山东中医杂志》
2018年第8期684-687,共4页
Shandong Journal of Traditional Chinese Medicine
基金
国家自然科学基金(编号:81503252)
山东省重点研发计划项目(编号:2017GSF19105)
山东省自然科学基金(编号:ZR2015HM080,ZR2014HQ005)
关键词
莱菔子
化学成分
提取分离
结构鉴定
Raphani Semen
chemical composition
extraction and separation
structure determination