壮药治疗肝脏疾病的研究进展

Research progress of liver disease treatment by Zhuang medicines

肝脏疾病目前已成为世界第五大致死疾病,且发病率逐年上升。数据显示,中国是病毒性乙型肝炎高发国家,约1/4的患者最终发展为慢性肝病,病情形势严峻。肝脏疾病的防治是医学科学重点研究对象之一,寻找疗效确切的具有抗病毒及免疫调节作用的天然药物已成为当今时下热点。壮药是壮族先民在壮医理论的基础上通过反复实践并加以运用的传统药物。历经长期的实验和临床研究,壮药在治疗肝病方面取得了一定进展,对肝病病毒具有显著的诱导及抑制作用,相较于现代医学的治疗在抗病毒、降酶、调节免疫、阻断病情进展等方面具有一定优势。该研究将从壮药的有效成分、有效部位、提取物及复方制剂治疗肝病的作用及其机制等方面的实验研究进展进行综述,为壮药治疗肝病研究与发展前景提供参考。

Liver disease has become the world＇s fifth deadliest disease,and its incidence is increasing year by year. According to official data,viral hepatitis is high incidence in China,the condition is grim that a quarter of the patients can develop into chronic liver disease. Liver disease prevention is one of the key research topic of medical science,searching for the natural medicines of helping treat virus and human immunity has become the research focuses in current medical science field. Zhuang medicines were developed from Zhuang medical theory and practice,which are the traditional medicine used by Zhuang ancestors. The long period of experiments and clinical researches suggest that Zhuang medicines have therapeutic effects for liver disease and significant inhibitory effects on liver virus. Compared with modern medical therapy in the treatment of liver disease,Zhuang medicines therapy have more advantages in virus resistance,enzyme activity reducing,immunity improving and disease control. This study provides the overview of therapeutic effect and its mechanism on liver disease from active ingredients,effective parts,extracts and compound preparation,to provide reference for the study of Zhuang medicines＇ therapeutic effects on liver disease and research progress.