射血分数降低和射血分数保留的急性心力衰竭患者远期预后探究

Long-term Prognosis of Acute Heart Failure Patients with Reduced Ejection Fraction and Blood Fraction Retention

目的:分析射血分数降低和射血分数保留的急性心力衰竭患者远期预后。方法:选择2014年1月~2016年12月在某院接受治疗的急性心力衰竭患者105例,按照射血分数降低及射血分数保留将患者分成两组,即AHFrEF组(55例)及AHFpEF组(50例),收集并分析患者从入院至出院后随访24个月之间的临床资料,以该患者死亡或再次住院为截至时间。结果:AHFrEF组患者及AHFpEF组患者高血压患病率、COPD患病率、ACS患病率以及BNP水平等指标比较组间差异均比较明显(P<0.05);AHFrEF组及AHFpEF组再次住院原因是脑卒中、ACS以及恶性心律失常,发生几率差异均比较明显(P<0.05);高血压、BNP均是造成ANF的危险因素;AHFrEF组患者中由于心力衰竭引发的再次住院率以及总再次住院率均高于AHFpEF组患者(P<0.05);AHFrEF组患者12个月、24个月生存率分别为98.18%(54/55)、94.55%(52/55),AHFpEF组患者12个月、24个月生存率分别为98.00%(49/50)、94.00%(47/50),两组差异无显著性(P>0.05)。结论:高血压及过高的BNP可能与AHF患者再次住院有关,因此应加强对AHF患者随访工作,特别是合并高血压的患者,需提高对血压的控制。

Objective：To analyze the long-term prognosis of acute heart failure patients with reduced ejection fraction and blood fraction retention.Methods：105 cases of patients with acute heart failure in a hospital for treatment from January 2014 to December 2016 were divided into two groups as AHFrEF group （55 cases） and AHFpEF group （50 cases）according to thee jection fraction reduction and ejection fraction reservation,clinical data of patients were collected and analyzed from admission to discharge for a follow-up period of 24 months,regarde dpatients＇ death or second hospitalization as the cut time.Results：The prevalence of high blood pressure,the prevalence of COPD,the incidence of ACS and the BNP level were significantly different in AHFrEF group and AHFpEF group （P〈0.05）.The reasons for there hospitalization of AHFrEF group and AHFpEF group were there sult of cerebral apoplexy,ACS and malignant arrhythmias,which were significant lyevident（less than 0.05）.Hypertension and BNP are both risk factors for ANF.In the AHFrEF group, there hospitalization rate caused by heart failure and the to talre hospitalization rate were higher than those in the AHFpEF group （P〈0.05）.AHFrEF patients for 12 months and 24 months survival rates were 98.18%（54/55）,94.55%（52/55）,AHFpEF patients for 12 months and 24 months survival rates were 98.00%（49/50）,94.00%（47/50）,differences were not significant （P〉0.05）.Conclusion：Hypertensive and high BNP may be associated with patients with AHF rehospitalization,so it is important to streng then the follow-up of patients with AHF,especially those with hypertension,and the control of blood pressure should be improved.