尿微量白蛋白和尿糖检测对糖尿病早期肾损伤的临床意义分析

Clinical Significance of Urinary Microalbumin and Urine Glucose in Early Renal Injury in Diabetes Mellitus

目的分析尿微量白蛋白和尿糖检测对糖尿病早期肾损伤的临床意义。方法选取我院2015年4月~2018年3月53例2型糖尿病早期肾损伤患者作为观察组,选取同期50例健康体检者作为对照组,对比两组受检者尿微量白蛋白和尿糖检测结果。结果观察组患者尿微量白蛋白阳性率、尿糖阳性率分别为94.34%、92.45%,均高于对照组的4.00%、6.00%,组间比较,差异具有统计学意义(P<0.05)。观察组尿糖含量、尿微量白蛋白含量分别为(1.99±0.74)mmol/L、(42.56±7.46)mg/L,均高于对照组的(1.03±0.20)mmol/L、(12.89±3.87)mg/L,差异具有统计学意义(P<0.05)。结论糖尿病早期肾损伤患者体内环境发生明显变化,其尿微量白蛋白和尿糖含量均明显高于健康人群,及时对尿微量白蛋白和尿糖两种指标进行检测,对提示糖尿病患者是否合并早期肾损伤具有重要作用。

Objective To analyze the clinical significance of urinary microalbumin and urine glucose in early renal injury of diabetes mellitus.Methods From April 2015 to March 2018,53 patients with early renal injury of type 2 diabetes mellitus were selected as observation group and 50 healthy person as control group at the same time.The results of urinary microalbumin and urine glucose were compared between the two groups.Results The positive rates of urinary microalbumin and urine glucose in the observation group were 94.34% and 92.45%,respectively,which were higher than those in the control group 4.00%,6.00%,the difference between the two groups was statistically significant（P〈0.05）.The levels of urine glucose and urinary microalbumin in the observation group were（1.99 ±0.74）mmol/L,（42.56 ±7.46）mg/L,respectively,which were significantly higher than those in the control group（1.03 ±0.20）mg/L,（12.89 ±3.87）mg/L,the difference was statistically significant（P〈0.05）.Conclusion The contents of urinary microalbumin and urinary glucose in diabetic patients with early renal injury were significantly higher than those in healthy people.The timely detection of urinary microalbumin and urinary glucose was important to indicate whether diabetic patients complicated with early renal injury.