CRP和IGRA联合检测肺结核

COMBINING CRP AND IGRA TO TEST PATIENTS WITH PULMONARY TUBERCULOSIS

目的探讨血清CRP和IGRA联合检测对肺结核患者的临床应用价值。方法选择130名肺结核患者,依据痰液病原学细菌涂片检测的结果分为感染组和非感染组,测定两组患者的CRP和IGRA水平,比较CRP检测及CRP联合IGRA检测对肺结核患者早期诊断的灵敏度和特异度。结果单独检测CRP特异度为76.92%,灵敏度为83.33%;联合检测特异度86.54%,灵敏度92.31%。结论联合检测CRP和IGRA对肺结核患者的辅助诊断具有良好的临床应用价值。

Objective To explore the clinical value of combined detection of serum CRP and IGRA in pa tients with pulmonary tuberculosis. Methods 130 patients with pulmonary tuberculosis were selected and divided into infected group and non infected group according to the results of sputum bacterial smear test. The levels of CRP and IGRA were determined in two groups of patients. The early diagnosis of pulmonary tuberculosis was compared by CRP and CRP combined with IGRA. The sensitivity and specificity. Results The specificity of CRP was 76.92% and the sensitivity was 83.33%. The combined detection specificity was 86.54% and the sensitivity was 92.31%. Conclusion The combined detection of CRP and IGRA has a good clinical application value in the diagnosis of pulmonary tuberculosis patients.