显微取精术对无精子症患者性功能的影响

Effect of microsurgical testicular sperm extraction on the sexual function of patients with azoospermia

目的:研究非梗阻性无精子症患者行睾丸显微取精术后,患者血清性激素水平和性功能的变化。方法:采用自身对照的方法 ,从我院拟行辅助生殖助孕的患者中筛选出98例非梗阻性无精子症患者,行睾丸显微取精术,手术前及术后3个月分别进行血清性激素水平检测同时采用国际勃起功能指数调查问卷(IIEF-5问卷)评价受试者的勃起功能状况,并进行对比分析。结果:(1)手术前后患者体内的性激素(FSH、LH、Tr)水平差异无统计学意义(P>0.05);(2)患者的勃起功能指数在治疗前后差异有统计学意义(P<0.05);(3)两组患者焦虑、抑郁评分在治疗前后相比差异有统计学意义(P<0.05)。结论:睾丸显微取精术并未对患者体内的性激素水平造成明显影响,但手术给患者的勃起功能以及心理状况有显著性的影响。

Objective： To study the changes in serum sex hormones and sexual function in patients with nonobstructive azoospermia who undergoing microsurgical testicular sperm extraction. Methods： 98 patients with nonobstructive azoospermia to receive assisted reproduction were selected for microsurgical testicular sperm extraction.The preoperative and 3-month postoperative serum sex hormone levels were detected while the international index of erectile function questionnaire（ IIEF-5 questionnaire） was surveyed to evaluate the erectile function. Results：（1）Difference in sex hormone（ FSH,LH,Tr） in patients between before and after surgery was not significant（ P 〈 0. 05）;（2）Difference in index of erectile function in patients between before and after treatment was statistically significant（ P 〈 0. 05）;（3）Differences in anxiety and depression scores between before and after treatment were statistically significant in both groups（ P 〈 0. 05）. Conclusions： Microsurgical testicular sperm extraction exerts no significant effect on the level of sex hormones in patients,but the operation has a significant impact on the erectile function and psychological status.