外周动脉疾病的治疗进展

Progress in the Treatment of Peripheral Artery Diseases

外周动脉疾病(PAD)与吸烟、糖尿病等关系密切,随着诊断技术的逐步提升,PAD的治疗也在不断变化。目前PAD的治疗主要有药物治疗、干细胞治疗、血运重建治疗及运动和电刺激治疗。PAD的药物治疗以抗血小板为主,通过抗血小板治疗可抑制血小板聚集,减少缺血风险,改善下肢缺血症状,还可以降低患者心血管不良事件的发生率。干细胞治疗可以从已经存在的血管诱导生成新的血管。血运重建治疗可以恢复血流,明显减少截肢事件的发生。运动治疗和电刺激治疗可以改善患者运动能力,改善生活质量和功能状态。

Peripheral arterial disease（ PAD） is closely related to smoking,diabetes and so on. With the gradual improvement of diagnostic technology,the treatment of PAD is also changing. At present,the treatment of PAD includes drug therapy,stem cell therapy,revascularization therapy,exercise and electrical therapy. The drug treatment of PAD is mainly antiplatelet,which can inhibit platelet aggregation,reduce the risk of ischemia,improve the symptoms of lower limb ischemia,and reduce the incidence of adverse cardiovascular events in patients. Stem cell therapy can induce new blood vessels from existing vessels. Revascularization can restore blood flow and significantly reduce amputation events. Exercise therapy and electrical stimulation therapy can improve exercise capacity,quality of life and functional status of the patients.