利格列汀联合二甲双胍治疗2型糖尿病的临床疗效

Clinical Curative Effect of Linagliptin Combined with Melbine in Treatment of Type 2 Diabetes

目的分析利格列汀联合二甲双胍治疗2型糖尿病的具体效果。方法将2015年1月—2018年1月在该院进行治疗的40例患者分为观察组和对照组,各20例,对照组单纯使用二甲双胍进行治疗,观察组患者使用利格列汀联合二甲双胍进行治疗,对比两组的治疗效果。结果观察组治疗后FPG、2 hPG、BMI、HbAlc各项指标均优于对照组,差异有统计学意义(P<0.05)。结论 2型糖尿并患者使用利格列汀联合二甲双胍治疗的效果较为理想,能够帮助患者控制血糖的平稳,且发生低血糖的几率较低,用药的安全性较高,值得在临床上进行推广使用。

Objective To analyze the specific effect of linagliptin combined with melbine in treatment of type 2 diabetes.Methods 40 cases of patients treated in our hospital from January 2015 to January 2018 were selected and divided into two groups with 20 cases in each, the control group were only treated with melbine, while the observation group were treated with linagliptin combined with melbine, and the treatment effect was compared between the two groups. Results After treatment, the FPG, 2 hPG, BMI, HbAlc in the observation group were better than those in the control group, and the differences were obvious, with statistical significance（P〈0.05）. Conclusion The effect of linagliptin combined with melbine in treatment of type 2 diabetes patients is ideal, which can help patients control the stability of blood glucose, with lower occurrence probability of hypoglycemia and higher medication safety, and it is worth promotion and application in clinic.