虹膜松弛综合征的研究进展

Progress on intraoperative floppy iris syndrome

虹膜松弛综合征是白内障患者行超声乳化手术过程中出现的虹膜松弛呈波浪状起伏、涌动、虹膜易有向切口脱出的倾向以及充分散瞳后术中仍出现渐进性瞳孔缩小的三联征。大量研究表明其与白内障患者术前使用α-受体阻滞剂密切相关。本文就虹膜松弛综合征的起源与流行病学、病因及其发病机制、临床表现、相关手术并发症以及其预防及治疗措施进行综述。

Intraoperative floppy iris syndrome（ IFIS） is a triad intraoperative abnormality of phacoemulsification. It is characterized by flaccid,undulating and billowing iris stroma,a tendency to prolapse toward the incisions,and progressive pupil constriction despite standard preoperative pharmacologic measures. Many researches have demonstrated that IFIS is associated with the use of tamsulosin,a systemic sympathetic α-1 adrenergic receptor antagonists. This paper reviews the origin and epidemiological characteristics,risk factors and pathogenesis,clinical manifestations,complications,and prophylaxis and treatment of the intraoperative floppy iris syndrome.