卤米松和氢化可的松乳膏治疗神经性皮炎的临床疗效对比

Comparison of Clinical Efficacy of Halogen and Hydrocortisone Cream in the Treatment of Neurodermatitis

目的:针对神经性皮炎患者分别采用卤米松乳膏和氢化可松乳膏治疗,对比分析临床效果和安全性。方法:选取江西省萍乡市皮肤病专科医院2017年11月至2018年3月收治的60例神经性皮炎患者,按照随机数字法分成两组,实验组30例,对照组30例。实验组患者采用0.05%卤米松乳膏进行治疗,对照组患者采用0.05%氢化可松乳膏治疗,2周为一个疗程。对比两组患者治疗有效率、不良反应发生率、药物起效时间。结果:实验组患者的治疗有效率显著高于对照组,不良反应发生率显著低于对照组,药物起效时间显著短于对照组,两组对比差异显著,P<0.05,统计学有意义。结论:对于神经性皮炎患者,采用卤米松乳膏治疗的效果要优于氢化可松乳膏,而且治疗更安全,药物起效更快,该药物更适合在临床中推广使用。

Objective To compare the clinical efficacy and safety of halomethasone cream and hydrocortisone cream in patients with neurodermatitis.Methods： Sixty patients with neurodermatitis treated in our hospital from November 2017 to March 2018 were selected and divided into two groupsaccording to the random number method. The experimental group included 30 cases and the control group included 30 cases. The patients in theexperimental group were treated with 0.05% halomethasone cream, while the patients in the control group were treated with 0.05% hydrocortisonecream for 2 weeks. The effective rate of treatment, the incidence of adverse reactions and the onset time of the drug were compared between the twogroups. Results： The effective rate in experimental group was significantly higher than that of the control group; the incidence of adverse reactionswas significantly lower than that of the control group; and the effective time of the drug was significantly shorter than that of the control group. Thedifference between the two groups was significant （P〈0.05）. Conclusion： For patients with neurodermatitis, halomethasone cream is more effectivethan hydrocortisone cream.