气相色谱-三重四极杆串联质谱法对甜瓜中11种农药残留的测定

Determination of 11 kinds of pesticide residues in melon by gas chromatography-triple quadrupole tandem mass spectrometry

目的建立用气相色谱-串联质谱联用法检测甜瓜中甲胺磷等11种农药残留的分析方法。方法样品用QuEChERS法提取,经MgSO_4、PSA净化,气相色谱-串联质谱法测定,外标法定量。结果 11种农药在添加浓度为0.05、0.10、0.20 mg/kg水平时具有良好的线性关系,相关系数均大于0.991,回收率为80.10%~111.30%,相对标准偏差(relative standard deviation,RSD)范围为1.32%~11.00%,检出限在0.0003~0.01 mg/kg。结论该方法简便、快捷,准确性、精确性和灵敏度均满足农药残留分析的要求。

Objective To establish a method for the determination of 11 kinds of pesticide residues such as methamidophos in melon by gas chromatography-tandem mass spectrometry. Methods The samples were extracted by QuEChERS method, purified by MgSO_4 and PSA, determined by gas chromatography-tandem mass spectrometry, and quantified by external standard method. Results There were a good linear relationship between the 11 kinds of pesticides at the concentration of 0.05、0.10、0.20 mg/kg, and the correlation coefficient was greater than 0.991. The recovery rates at the added concentration level were 80.10%-111.30%, the relative standard deviations（RSDs） range were 1.32%-11.00%, and the limits of detection were 0.0003-0.01 mg/kg. Conclusion This method is simple and rapid, its accurate, accurate and sensitive all meet the requirements of pesticide residue analysis.