不同性别骨密度与血脂、血糖、血压的相关性研究

Correlation research among blood lipids,blood glucose,blood pressure and bone mineral density in difference gender

目的探讨不同性别健康体检人群骨密度与血脂、血糖、血压的相关性。方法重庆市3 456名健康体检人群,测量骨密度、血脂和血糖、身高、体质量、血压,根据骨密度结果将体检者分为骨密度正常组和骨密度异常组,分析不同性别骨密度与血脂、血压、血糖的相关性。结果女性骨密度正常者占31.2%,男性骨密度正常者占29.9%,女性骨密度异常者占29.5%,男性骨密度异常者占9.4%。女性骨密度异常率高于男性(P<0.05),女性骨密度异常组的年龄、空腹血糖、血压、三酰甘油、总胆固醇和低密度脂蛋白胆固醇(LDL-C)高于骨密度正常组,HDL-C和双股骨、腰椎(L1~4)骨密度明显低于骨密度正常组,男性骨密度异常组的年龄、血糖明显高于骨密度正常组,双股骨、腰椎(L1~4)骨密度明显低于骨密度正常组。进一步进行Pearson相关分析表明年龄、血糖、血压和血脂是女性骨密度下降的影响因素(P<0.05),年龄和体质量指数(BMI)是男性骨密度下降的影响因素,血脂、血压和血糖与男性骨密度无相关性(P>0.05)。结论女性的年龄、血糖、血压和血脂与骨密度下降存在着相关关系,男性的年龄和BMI与骨密度下降存在相关关系。

Objective To investigate the correlation among blood lipids,blood glucose,blood pressure and bone mineral density in healthy people of different gender. Methods 3 456 healthy people were selected,bone mineral density,blood lipids,blood glucose,height,weight and blood pressure were tested,and they were divided into the normal and abnormal groups according to bone mineral density,analyzed the correlation among blood lipids,blood pressure,blood glucose and bone mineral density in different gender. Results The normal bone mineral density in female was 31.2%,the male was 29.9%,the abnormal bone mineral density in female accounted for 29.5%,and the male accounted for 9.4%.Bone mineral density abnormal rate in female was significantly higher than that in male （ P 〈0.05）.Age,fasting blood glucose,blood pressure,triglyceride,total cholesterol and LDL-C of the abnormal group in female were significantly higher than those of the normal group,HDL-C,double femur and lumbar spine （L 1~4 ） bone mineral density were significantly lower than those of the normal group.The levels of age and blood glucose of the abnormal group in male were higher than those of the normal group,double femur and lumbar spine （L 1~4 ） bone mineral density were lower than those of the normal group.Pearson correlation analysis showed that age,blood glucose,blood pressure and blood lipids were the influence factors on bone mineral density loss in female （ P 〈0.05）,age and BMI were the influence factors in male,there were no correlation between blood lipids,blood pressure,blood glucose and bone mineral density in male （ P 〉0.05）. Conclusion Age,blood glucose,blood pressure and blood lipids are in correlation with bone mineral density loss in female,age and BMI are correlated with bone mineral density loss in male.