牙周再生术治疗慢性牙周炎不同程度骨缺损的疗效评价

Evaluation of bone regeneration in chronic periodontal patients with different degrees of bone defect

目的:探讨慢性牙周炎不同程度骨缺损且非植骨适应症的患牙经牙周再生术后的临床疗效。方法:选取26例共35个慢性牙周炎非植骨适应症的浅骨袋患牙,利用术前影像测量骨袋底到釉牙骨质界的距离(A-CEJ),将骨缺损分为轻度(3～6 mm)(n=15)、中度(6～9 mm)(n=11)、重度(9～12 mm)(n=9)。分别于牙周基础治疗后行牙周再生术,并于术前及术后6、12个月检查记录A-CEJ、牙周探诊深度(PD)、牙周临床附着丧失(CAL)。结果:牙周再生术后6、12个月,轻、中、重度骨缺损组A-CEJ较术前均明显降低(P<0.05),且骨缺损程度与牙周再生术后骨增量呈线性相关(P<0.05);术后12个月,中、重度骨缺损组PD、CAL较术前均明显降低(P<0.05),但骨缺损程度与PD、CAL无相关性(P>0.05)。结论:牙周再生术治疗慢性牙周炎轻、中、重度骨缺损的非植骨适应症患牙,能有效修复牙槽骨组织缺损,促进骨再生以及牙周附着的形成。

AIM： To evaluate the clinical effects of bone regeneration surgery in the treatment of periodontal bone defect（PBD） in the patients with chronic periodontitis（CP）. METHODS： 35 teeth with CP and PBD and without grafting indication were divided into 3 groups by A - CEJ （mm） ： mild （ 3 - 6, n = 15 ）, moderate （6 - 9, n = 11 ） and se- vere （9 -12 ,n = 9）, the patients were freated by periodental non -surgical trerapy followed by bone regeneration thera- py. Before and 6 and 12 months after treatment periodontal depth （PD） and periodontal clinical attachment loss （CAL） were measured and compared. RESULTS： 6 and 12 months after treatment A -CEJ increased（ P 〈 0.05 ） and PD and CAL decreased （ P 〈 0. 05 ） in all patients ; CAL decreased in the patients with moderate and severe bone defect （P 〈 0.05 ）. CONCLUSION： Bone regeneration can promote bone regeneration and the formation of new periodontal bone attachment of the teeth with moderate and severe bone defect.