新生儿B族溶血性链球菌感染情况及其危险因素Logistic回归分析

Infection status of group B hemolytic streptococci in neonates and Logistic regression analysis of its risk factors

目的调查新生儿B族溶血性链球菌(GBS)感染的情况,并分析其危险因素。方法对我院500例新生儿的GBS感染情况进行调查,对其危险因素进行Logistic回归分析。结果新生儿GBS感染率为6.40%,死亡率为6.25%;感染组出生日龄≥3 d、出生体质量<2 500 g、早产、羊水污染、母亲阴道深部GBS感染、母亲入院时破膜、孕晚期母亲有性行为史比例高于非感染组(P<0.05)。且上述因素均是GBS感染的独立危险因素(P<0.05)。结论新生儿GBS感染率和死亡率均较高,临床医生应根据研究结果对孕产妇加强健康宣教,制定针对性的预防策略。

Objective To investigate the infection status of group B hemolyt ic streptococcus（GBS） in neonates and analyze the risk factors. Methods The occurrence of GBS infection in 500 cases of newborns in our hospital were investigated, and Logistic regression analysis was carried out on the risk factors of GBS infection. Results The GBS infection rate in neonates was 6.40%, and the mortality rate was 6.25%. The ratios of birth daily age 3 d, birth body weight 2 500 g, premature birth, amniotic fluid pollution, deep GBS infection in mother vagina, membrane broke at admission, mother had sexual behavior in the late pregnancy of the infection group were significantly higher than those of the non-infection group（P〈0.05）, and above factors were independent risk factors for GBS infection（P〈0.05）.Conclusion The newborns have high rates of GBS infection and mortality. Clinicians should strengthen health education for pregnant women based on the results of the study and develop targeted prevention strategies.