无创正压通气对阻塞性睡眠呼吸暂停低通气综合征患者生命质量的影响

Effect of noninvasive positive pressure ventilation on quality of life in patients with obstructive sleep apnea hypopnea syndrome

目的观察无创正压通气对阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者生命质量的影响。方法 98例中、重度OSAHS患者随机分为对照组、试验组,分别行一般治疗和无创正压通气3个月,采用Epworth嗜睡量表(ESS)、Calgary睡眠呼吸暂停生活质量指数(SAQLI)评价疗效。结果试验组治疗后ESS评分低于对照组(P<0.01),而SAQLI评分高于对照组(P<0.01)。结论无创正压通气可改善OSAHS患者日间嗜睡症状和生活质量。

Objective To observe the effect of non-invasive positive pressure ventilation（NIPPV） on the quality of life in patients with obstructive sleep apnea hypopnea syndrome（OSAHS）. Methods Ninety-eight patients with moderate and severe OSAHS were randomized to control and observation groups, and respectively received general treatment and NIPPV for 3 months. The clinical efficacy was evaluated by Epworth sleepiness score（ESS） and Calgary sleep apnea quality of life index（SAQLI）. Results Compared with control group, ESS was decreased but SAQLI increased after treatment in observation group（P〈0.01）. Conclusion NIPPV can improve the daytime sleepiness and quality of life in patients with OSAHS.