咔唑的溴化研究

Study on Bromination of Carbazole

咔唑类化合物在很多领域的应用研究受到了科学家的广泛关注,特别在有机光电分子器件、太阳能电池材料、彩色液晶材料等前沿科技领域,展现出广阔的应用前景。但由于咔唑环上的电性较强,目前的咔唑溴化方法很难得到高纯溴代咔唑单体。采用氮酰基化保护,改变芳香环上的电子云分布,增强溴代选择性,通过H_2O_2-HBr氧化溴化体系,合成两种不同取代的溴代咔唑,考察了合成温度、反应时间及物料配比等因素对反应的影响,利用熔点和~1H-NMR对产物进行表征。

Carbazole compounds in many fields of applied research attention by scientists, especially in organic photovoltaic devices, solar battery materials, color liquid crystal materials, and other areas of the frontier science and technology, show a broad application prospect. However, due to the strong electrical properties on the carbazole ring, it is very difficult to obtain the high purity bromo-carbazole monomer. Article acetoxylation with nitrogen protection, change the electron cloud distribution of aromatic ring, enhance selective bromide generation, by H2O2 oxidation-gets bromide system, synthesis of two different substituted bromine generation of carbazole, examines the synthetic temperature, the reaction time and the ratio of material and other factors on the reaction, the effect of using the melting point and 1 H-NMR of the product were characterized.