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慢性丙型肝炎患者血清自身抗体检测及其临床意义研究现状 被引量:6

Serum autoantibodies in patients with hepatitis C
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摘要 经常发现慢性丙型肝炎病毒(HCV)携带者血清非器官特异性自身抗体(non-organ-specific autoantibodies,NOSA)和抗甲状腺自身抗体(anti-thyroid autoantibodies ATAB)阳性,伴有以自身免疫耐受性丧失为特征的一组自身免疫性疾病,本文将重点介绍这方面的研究进展。 Serum non-organ-specific autoantibodies(NOSA) and anti-thyroid autoantibodies(ATAB) were often found positive in patients with chronic hepatitis C and hepatitis C viral carriers.The patients were characterized by loss of autoimmune tolerance,which might cause a set of autoimmune diseases in this setting.The progress in this field will be discussed in this article.
作者 姜宏达 周海舟 Jiang Hongda;Zhou Haizhou(Harbin Medical University,Harbin 150081,Heilongjiang Province,China)
出处 《实用肝脏病杂志》 CAS 2018年第5期817-820,共4页 Journal of Practical Hepatology
基金 黑龙江省科学技术研究发展计划项目(编号:2016D02-11)
关键词 丙型肝炎 自身免疫 抗体抗核 自身免疫性甲状腺疾病 干扰素-Α Hepatitis C Autoimmunity Antinuclear antibodie Autoimmune thyroid diseases Interferon-alpha
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  • 1Fried MW, Shiffman ML, Reddy KR, Smith C, Marinos G,Goncales FL Jr, Haussinger D, Diago M, Carosi G, Dhumeaux D, Craxi A, Lin A, Hoffman J,Yu J. Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection. N Engl J Med 2002; 347:975-982.
  • 2Fattovich G, Giustina G, Favarato S, Ruol A. A survey of adverse events in 11241 patients with chronic viral hepatitis treated with alpha interferon. J Hepatol 1996; 24:38-47.
  • 3Daleko$ GN, Christodoulou D, Kistis K, Zervou EK, Hatzis J,Tsianos EV. A prospective evaluation of dermatological sideeffects during alpha-interferon therapy for chronic viral hepatitis. Eur J Gastroenterol Hepatol 1998; 10:933-939.
  • 4Clifford BD, Donahue D, Smitt~ L, Cable E, Luttig B, Manns M, Bonkovsky HL. High prevalence of serological markers of autoimmunity in patients with chronic hepatitis C. Hepatology 1995; 21:613-619.
  • 5Noda K, Enomoto N, Arai K, Masuda E, Yamada Y, Suzuki K,Tanaka M, Yoshihara H. Induction of antinuclear antibody after interferon therapy in patients with type-C chronic hepatitis: its relation to the efficacy of therapy. Scand J Gastroenterol 1996; 31:716-722.
  • 6Cassani F, Cataleta M, Valentini P, Muratori P, Giostra F, Francesconi R, Muratori L, Lenzi M, Blanch G, Zauli D, Bianchi FB. Serum autoantibodies in chronic hepatitis C: comparison with autoimmune hepatitis and impact on the disease profile.Hepatology 1997; 26:561-566.
  • 7Muratori P, Muratori L, Verucchi G, Attard L, Bianchi FB,Lenzi M. Non-organ-specific autoantibodies in children with chronic hepatitis C: clinical significance and impact on interferon treatment. Clin Infect Dis 2003; 37:1320-1326.
  • 8Agarwal N, Handa R, Acharya SK, Wali JP, Dinda AK,Aggarwal P. A study of autoimmune markers in hepatitis Cinfection. Indian J Med Res 2001; 113:170-174.
  • 9Wada M, Kang KB, Kinugasa A, Shintani S, Sawada K, Nishigami T, Shimoyama T. Does the presence of serum autoaritibodies influence the responsiveness to interferon-alpha 2a treatment in chronic hepatitis C? Intern Med 1997; 36:248-254.
  • 10Wasmuth HE, Stolte C, Geier A, Dietrich CG, Gartung C,Lorenzen J, Matern S, Lammert F. The presence of non-organspecific autoantibodies is associated with a negative response to combination therapy with interferon and ribavirin for chronic hepatitis C. BMC Infectious Diseases 2004; 4:4-12.

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