脑室腹腔分流术后继发迟发性颅内血肿的相关因素分析

To analysis the related factors of delayed intracranial hematoma secondary to ventriculo-peritoneal shunt

目的脑室腹腔分流术后继发迟发性颅内血肿是临床上较为罕见但严重影响患者预后的并发症。本研究旨在探讨脑室腹腔分流术后继发迟发性颅内血肿的相关因素。方法回顾性分析笔者所在两家医院2007年5月至2017年5月收治的278例行脑室腹腔分流术患者,采用单因素及二元Logistic回归分析方法明确脑室腹腔分流术后继发迟发性颅内血肿的相关因素。结果共有9例患者于术后3 ～14天发生迟发性颅内血肿。单因素分析提示年龄,吸烟,高血压既往史,术后CT征象等与脑室腹腔分流术后继发迟发性颅内血肿相关(P<0.05)。二元Logistic回归分析提示术后CT征象是脑室腹腔分流术后继发迟发性颅内血肿的独立危险因素(P<0.05)。结论正确认识并重视影响脑室腹腔分流术后继发迟发性颅内血肿的相关因素,实施相应的临床干预措施,对于改善患者预后具有十分重要的意义。

Objective The delayed intracranial hematoma secondary to ventriculo-peritoneal shunt is a rare and serious complication.The purpose of this study is to investigate the related factors of delayed intracranial hematoma secondary to ventriculo-peritoneal shunt.MethodsThe clinical data of 278 patients who underwent ventriculo-peritoneal shunt during 2007.05 to2017.05 were analysised retrospectively.The clinical variables were examined by univariate analysis and binary logistic regression analysis to identify the related factors of delayed intracranial hematoma secondary to ventriculo-peritoneal shunt.Results There were 9 patients suffering from delayed intracranial hematoma between 3 and 14 days after surgery.The univariate analysis indicated that age,smoking,history of hypertension and postoperative CT characteristics were related to delayed intracranial hematoma（P0.05）.The binary Logistic regression analysis indicated that postoperative CT characteristics was an independent risk factor for delayed intracranial hematoma secondary to ventriculo-peritoneal shunt（P0.05）.Conclusion It is important to pay more attention to the related factors of delayed intracranial hematoma secondary to ventriculoperitoneal shunt and implement the corresponding clinical interventions.Only in this way,improving the prognosis of patients ispossible.