视网膜静脉阻塞与颈动脉血液流变学的相关性

Relationship between retinal vein occlusion and hemorheology of carotid artery

目的 研究颈动脉血液流变学与视网膜静脉阻塞的发病及预后的相关性.方法 2016年8月至2017年5月,视网膜静脉阻塞（RVO）30例（30眼）,作为病例组;以同期就诊的非RV0 30例为对照组（30只健眼）.比较有关指标在两组之间的差异.结果 病例组和对照组的颈动脉超声异常率分别为56.7％ （17/30）、6.7％ （2/30）,差异有统计学意义（P =0.000）.病例组与对照组相比,患眼侧的颈内动脉收缩期峰值（PSV）和舒张末期速度（EDV）显著降低,阻力指数（RI）明显升高,差异均有统计学意义（P =0.000,0.000,0.000）.患眼侧与对侧健眼的颈内动脉血液流变学指标之间差异无统计学意义（P=0.32,0.11,0.20）.随访6个月后,视力好转者颈内动脉的EDV有所增加,RI有所降低,视力恶化者则相反.结论 颈动脉血液流变学与视网膜静脉阻塞的发病及预后之间具有相关性,应尽早发现颈动脉血液流变学异常,预防或降低视网膜静脉阻塞疾病的风险.

Objective To study the relationship between the incidence and prognosis of retinal vein occlusion and carotid blood rheology.Methods From Aug.2016 to May 2017,30 eyes of 30 patients with retinal vein occlusion （RVO） were enrolled as the case group;in the same period,30 eyes of 30 health cases with non-RVO and no other fundus vascular lesions was collected as the control group.The relevant indexes of two groups were compared.Results The ultrasound abnormal rate of carotid artery in the case group and the control group were 56.7% （17/30） and 6.7% （2/30） respectively,and the difference was statistically significant （P =0.000）.Compared with the control group,the peak systolic velocity （PSV） and end-diastolic velocity （EDV） of the internal carotid artery were decreased,and resistance index （RI） increased.The difference in the carotid artery hemorheology index were statistically significant （P =0.000,0.000,0.000）.The difference index of hemorroeodoge was not significant between sick eyes and health eyes （P =0.32,0.11,0.20）.After 6 months follow-up,the EDV of the patients with improved visual acuity was increased,and the RI decreased,while the patients with impaired vision were the opposite.Conclusion Carotid artery blood rheology is correlated with the incidence and prognosis of retinal vein occlusion.Abnormal carotid blood rheology should be found as soon as possible,to prevent or reduce the risk of retinal vein occlusion.