摘要
细胞程序性死亡作为一种生理性的死亡,受到不同信号通路的控制。各种信号通路之间也存在着联系,作用不足或过激都会对细胞产生影响,从而造成身体病变。其中心肌细胞程序性死亡与心脏相关疾病存在密切联系。明确信号通路对细胞程序性死亡的调控作用对心脏相关疾病的诊断及治疗具有指导意义。
Programmed cell death as a physiological death, is controlled by different signal pathways. There is a link between various signaling pathways. If the effect of this relationship is insufficient or excessive, it will have an impact on cells, resulting in physical changes. Among them, there is a close relationship between programmed cardiomyocytes death and is important heart-related diseases. The regulation of signal pathway on programmed cell death for the diagnosis and treatment of heart-related diseases.
作者
辛庆龄
徐伟男
刘聪颖
李悦
王茎
XIN Qingling;XU Weinan;LIU Congying;LI Yue;WANG Jing(Anhui University of Chinaese Medicine,Hefei 230038,China)
出处
《长春中医药大学学报》
2018年第4期772-775,共4页
Journal of Changchun University of Chinese Medicine
基金
国家自然科学基金(81574084)
安徽省自然基金(1608085MH230)
安徽中医药大学科学研究基金(2018zrzd01)
关键词
细胞程序性死亡
信号通路
心肌细胞
programmed cell death
signaling pathway
cardiomyocytes