2005—2017年天津市东丽区疑似预防接种异常反应监测分析

Analysis on surveillance of adverse events following immunization in Dongli District of Tianjin from 2005-2017

目的分析2005—2017年天津市东丽区疑似预防接种异常反应(AEFI)监测资料,评价AEFI信息管理系统运转情况。方法采用描述流行病学方法对2005—2017年天津市东丽区AEFI报告个案信息进行统计分析。结果 2005—2017年天津市东丽区共报告AEFI个案1 118例,分布于8个街道。总发生率为38.66/10万剂次,异常反应发生率为5.22/10万剂次。2岁以内AEFI发生数最高,占全部反应的66.1%。五联疫苗的AEFI报告发生率最高为346.02/10万剂次。结论 2005—2017年天津市东丽区AEFI主要发生在小年龄组和免疫接种1天内,今后应继续加强对AEFI监测的培训工作,提高AEFI监测工作的敏感性与报告的及时性。

[Objective]To analyze the adverse events following immunization（AEFI） surveillance data in Dongli District of Tianjin from 2005-2017,and evaluate the operation of AEFI information management system. [Methods] The descriptive epidemiological method was used to analyze AEFI data in Dongli District of Tianjin from 2005-2017. [Results] From 2005-2017,1 118 cases of AEFI were reported in Dongli District,distributed in 8 subdistricts. The total incidence was 38.66/100 000 doses,and the incidence of AEFI was 5.22/100 000 doses. Most AEFI were children under 2 years,accounted for 66.1% of the total cases. The incidence rate of DTa P-IPV/Hib was highest（346.02/100 000 doses）. [Conclusion] Most AEFI cases are children of low age group and within 1 day after vaccination in Dongli District of Tianjin from 2005-2017. In the future,it is necessary to further strengthen the training of AEFI surveillance,and improve the sensitivity and timeliness of AEFI surveillance.