康复新液防治宫颈癌放疗所致皮肤黏膜损伤的效果及护理

Effect of Kangfuxin solution in prevention and treatment of radiotherapy-induced skin and mucosa reaction of patients with cervical cancer and related nursing management

目的探讨康复新液冲洗会阴部防治宫颈癌放疗所致皮肤黏膜损伤的效果,总结患者心理护理措施。方法 128例宫颈癌放疗患者随机分为观察组和对照组,各64例。对照组采用生理盐水冲洗会阴。观察组给予康复新液冲洗会阴部,治疗期间联合针对性心理干预。比较2组放疗30 Gy时和放疗结束后皮肤损伤程度和疼痛程度,观察2组干预前后睡眠质量和焦虑情况。结果观察组放疗30 Gy时和放疗结束后皮肤损伤程度和疼痛程度均低于对照组(P<0.05)。干预后,观察组匹兹堡睡眠质量指数(PSQI)评分及焦虑自评量表(SAS)评分改善优于对照组(P<0.05)。结论康复新冲洗会阴部有利于预防和减轻放疗所致的会阴部皮肤损伤,减轻疼痛,同时联合心理干预能有效提高患者睡眠质量,缓解其焦虑情绪。

Objective To investigate the effect of perineal w ashing w ith Kangfuxin solution in prevention and treatment of radiotherapy-induced skin and mucosa reaction of patients w ith cervical cancer,and to summarize related psychological nursing measures. Methods Totally 128 cervical cancer patients undergoing radiotherapy w ere assigned to the observation group and the control group,w ith 64 cases in each group. Patients in the control group received perineal w ashing w ith normal saline to prevent radiotherapy-induced skin and mucosa reaction,and those in the observation group w ere given perineal w ashing w ith Kangfuxin solution. In addition,the targeted psychological nursing w as carried out in the observation group. The degree of perineal skin damage and pain w ere assessed at dose of 30 Gy and end of radiotherapy. The sleep quality and anxiety status of patients w ere compared betw een tw o groups. Results Patients of the observation group had a less severity of perineal skin damage and low er pain degree compared w ith those in the control group at dose of 30 Gy and end of radiotherapy,respectively（ P 〈0. 05）. After intervention,patients of the observation group achieved a better improvement of Pittsburgh Sleep Quality Index（ PSQI） and Self-rating Anxiety Scale（ SAS） compared w ith those of controls（ P 〈0. 05）. Conclusion The perineal w ashing w ith Kangfuxin solution is effective to prevent the radiotherapy-induced skin and mucosa reaction of patients w ith cervical cancer. It is also required to carry out psychological intervention to improve the sleep quality and mental status of patients during treatment.