上气道阻力综合征患者治疗前后心理变化的对比研究

A comparative study of psychological changes after treatment in patients with upper airway resistance syndrome

目的认识上气道阻力综合征(upper airway resistance syndrome,UARS)患者睡眠障碍治疗前后的临床心理变化,提高对上气道阻力综合征(UARS)患者治疗中,心理变化的认识,完善治疗方法。方法选择21例经多导睡眠监测和食道测压确诊的UARS患者,分析其主观量表指标,包括:嗜睡量表(Epworth Sleeping Scale,ESS),匹兹堡睡眠调查表(Pittsburgh sleep quality index,PSQI),汉密顿抑郁量表(Hamilton Depression Scale,HAMD)及焦虑量表(Hamilton Anxiety Scale,HAMA)评分进行量化比较;以及客观参数,包括:多导睡眠监测(Polysomnography,PSG)中的睡眠效率,N3时间百分比,呼吸努力相关微觉醒(respiratory effort related arousal,RERA)指数及客观警觉试验(OSLER Test)评估值,经个体化综合治疗3个月后,行前后对比分析。结果治疗前后主客观参数除客观警觉试验(OSLER Test)评估值以外,差异均有统计学意义。结论 UARS患者因长期睡眠问题可进一步影响情绪,引起心理改变,个体化综合治疗可以改善其心理状况。

Objective To comparate psychological changes after treatment in patients with upper airway resistance syndrome Methods The study randomly selected 21 UARS patients diagnosed by PSG and Esophageal pressure check. Analyze their subjective scale index, including ESS, PSQI, HAMD, HAMA; and their objective index, including PSG, and OSLER Test. The pre-and post-therapy clinical data of them were comparatively analyzed. Results There were significant differences pre-and post-therapy in subjective scale and objective index, except OSLER Test. Conclusion Chronic sleep disorders can further affect mood and cause psychological change in UARS patients, Individual comprehensive treatment can improve the psychological status.